virtualbox '/etc/init.d/vboxdrv setup'

You probably have setup virtualbox with some vm.
And you have just upgraded some of the latest patches (including kernel packages as well).

And after reboot, you try to start the vm, but it shows errors, and asking you to try run '/etc/init.d/vboxdrv setup' 

Resolution:

- make sure you have your latest kernel installed along with the kernel-headers,

Under Fedora

-

Under Ubuntu

- there will be no /etc/init.d/vboxdrv command.

- You will need to make sure packages below are installed:

$ sudo aptitude install dkms virtualbox-dkms

$ sudo aptitude install linux-headers-3.5.0-26

$ sudo aptitude install linux-headers-3.5.0-26-generic

$ sudo dpkg-reconfigure virtualbox-dkms

Reference:

http://askubuntu.com/questions/205154/virtualbox-etc-init-d-vboxdrv-setup-issue